Gender Differences in Rheumatic Heart Disease: Data from a District Hospital in Cirebon, Indonesia

Authors

  • Airin Alia Hikmayani Hasna Medika Cardiovascular Hospital
  • Yogi Puji Rachmawan Hasna Medika Cardiovascular Hospital
  • Witri Pratiwi Universitas Swadaya Gunung Jati

DOI:

https://doi.org/10.46799/jhs.v6i1.1464

Keywords:

gender, rheumatic heart disease, RHD, women, heart valve diseases

Abstract

Rheumatic heart disease (RHD) has a high prevalence in low- and middle-income countries, including Indonesia. Gender is among the sociodemographic factors that can influence RHD prevention and management strategies. This study aims to describe the clinical profile of RHD patients, with a focus on gender differences. This cross-sectional study was conducted at Hasna Medika Cardiovascular Hospital in Cirebon, Indonesia. This study included RHD patients in the outpatient clinics, either who came for routine treatment or were newly diagnosed with RHD. Patients’ demographic and clinical data were collected through medical records from January 2023 to December 2023. A total of 157 patients’ data were analyzed. RHD was more common in women (70.7%) than men (29.3%). The incidence of RHD in women was higher (27.9%) in the age group 60 years old and above than in men (19.6%). The most common valve involved in RHD was the mitral valve, more frequently in women (100%) than men (97.8%), with severe mitral stenosis being the most prevalent valve abnormality in both genders (52.3% in women, 47.8% in men). Women have a higher prevalence of RHD than men. This study emphasises the importance of education and the needed improvement of RHD management strategies, specifically for women, as they have a higher burden of RHD.

References

Pandian Ng, Kim Jk, Arias-Godinez Ja, Et Al. Recommendations For The Use Of Echocardiography In The Evaluation Of Rheumatic Heart Disease: A Report From The American

Society Of Echocardiography. Journal Of The American Society Of Echocardiography. 2023;36(1):3-28. Doi:10.1016/J.Echo.2022.10.009

Guan C, Xu W, Wu S, Zhang J. Rheumatic Heart Disease Burden, Trends, And Inequalities In Asia, 1990–2019. Glob Health Action. 2023;16(1):2215011. Doi:10.1080/16549716.2023.2215011

Watkins Da, Johnson Co, Colquhoun Sm, Et Al. Global, Regional, And National Burden Of Rheumatic Heart Disease, 1990–2015. New England Journal Of Medicine. 2017;377(8):713-722. Doi:10.1056/Nejmoa1603693

Muharram Fr, Multazam Cecz, Mustofa A, Et Al. The 30 Years Of Shifting In The Indonesian Cardiovascular Burden—Analysis Of The Global Burden Of Disease Study. J Epidemiol Glob Health. 2024;14(1):193-212. Doi:10.1007/S44197-024-00187-8

Zühlke L, Engel Me, Karthikeyan G, Et Al. Characteristics, Complications, And Gaps In Evidence-Based Interventions In Rheumatic Heart Disease: The Global Rheumatic Heart Disease Registry (The Remedy Study). Eur Heart J. 2015;36(18):1115-1122. Doi:10.1093/Eurheartj/Ehu449

Simpson Mt, Kachel M, Neely Rc, Et Al. Rheumatic Heart Disease In The Developing World. Structural Heart. 2023;7(6). Doi:10.1016/J.Shj.2023.100219

Sriha Belguith A, Koubaa Abdelkafi A, El Mhamdi S, Et Al. Rheumatic Heart Disease In A Developing Country: Incidence And Trend (Monastir; Tunisia: 2000–2013). Int J Cardiol. 2017;228:628-632. Doi:10.1016/J.Ijcard.2016.11.249

Kafle Rc, Alurkar Vm, Paudel N, Jha Gs. Pattern Of Valvular Involvement In Rheumatic Heart Disease Patients In A Tertiary Care Hospital Of Western Nepal. Nepalese Heart Journal. 2016;13(2):29-31. Doi:10.3126/Njh.V13i2.15561

Owusu Ik, Acheamfour-Akowuah E, Wiafe Ya. Clinical And Socio-Demographic Profiles Of Patients Seen With Rheumatic Heart Disease In A Cardiac Clinic Of A Tertiary Hospital In Ghana. Research Reports In Clinical Cardiology. 2022;Volume 13:85-93. Doi:10.2147/Rrcc.S372472

Negi Pc, Mahajan K, Rana V, Et Al. Clinical Characteristics, Complications, And Treatment Practices In Patients With Rhd: 6-Year Results From Hp-Rhd Registry. Glob Heart. 2018;13(4):267-274.E2. Doi:Https://Doi.Org/10.1016/J.Gheart.2018.06.001

Rudiktyo E, Wind A, Doevendans P, Siswanto Bb, Cramer Mj, Soesanto Am. Characteristics Of Patients With Rheumatic Heart Disease In A National Referral Hospital In Indonesia. Medical Journal Of Indonesia. 2022;31(3):178-185. Doi:10.13181/Mji.Oa.226150

Shi L, Bao C, Wen Y, Liu X, You G. Analysis And Comparison Of The Trends In Burden Of Rheumatic Heart Disease In China And Worldwide From 1990 To 2019. Bmc Cardiovasc Disord. 2023;23(1). Doi:10.1186/S12872-023-03552-W

Lv M, Jiang S, Liao D, Lin Z, Chen H, Zhang J. Global Burden Of Rheumatic Heart Disease And Its Association With Socioeconomic Development Status, 1990–2019. Eur J Prev Cardiol. 2022;29(10):1425-1434. Doi:10.1093/Eurjpc/Zwac044

Shimura T, Yamamoto M, Kano S, Et Al. Patients Refusing Transcatheter Aortic Valve Replacement Even Once Have Poorer Clinical Outcomes. J Am Heart Assoc. 2018;7(18). Doi:10.1161/Jaha.118.009195

Shrestha Nr, Pilgrim T, Karki P, Et Al. Rheumatic Heart Disease Revisited: Patterns Of Valvular Involvement From A Consecutive Cohort In Eastern Nepal. Journal Of Cardiovascular Medicine. 2012;13(11):755-759. Doi:10.2459/Jcm.0b013e32835854b6

Negi Pc, Kandoria A, Asotra S, Et Al. Gender Differences In The Epidemiology Of Rheumatic Fever/Rheumatic Heart Disease (Rf/Rhd) Patient Population Of Hill State Of Northern India; 9 Years Prospective Hospital Based, Hp-Rhd Registry. Indian Heart J. 2020;72(6):552-556. Doi:10.1016/J.Ihj.2020.09.011

Sani Mu, Karaye Km, Borodo Mm. Cardiovascular Topics Prevalence And Pattern Of Rheumatic Heart Disease In The Nigerian Savannah: An Echocardiographic Study. Vol 18. Www.Cvjsa.Co.Za

Ozer O, Davutoglu V, Sari I, Akkoyun Dc, Sucu M. The Spectrum Of Rheumatic Heart Disease In The Southeastern Anatolia Endemic Region: Results From 1900 Patients. J Heart Valve Dis. 2009;18(1):68-72. Http://Europepmc.Org/Abstract/Med/19301555

Movahed Mr, Ahmadi-Kashani M, Kasravi B, Saito Y. Increased Prevalence Of Mitral Stenosis In Women. Journal Of The American Society Of Echocardiography. 2006;19(7):911-913. Doi:10.1016/J.Echo.2006.01.017

Mutagaywa Rk, Wind Am, Kamuhabwa A, Cramer Mj, Chillo P, Chamuleau S. Rheumatic Heart Disease Anno 2020: Impacts Of Gender And Migration On Epidemiology And Management. Eur J Clin Invest. 2020;50(12). Doi:10.1111/Eci.13374

Kislitsina On, Zareba Km, Bonow Ro, Et Al. Is Mitral Valve Disease Treated Differently In Men And Women? Eur J Prev Cardiol. 2019;26(13):1433-1443. Doi:10.1177/2047487319833307

Carapetis Jr, Wolff Dr, Currie Bj. Acute Rheumatic Fever And Rheumatic Heart Disease In The Top End Of Australia’s Northern Territory. Medical Journal Of Australia. 1996;164(3):146-149. Doi:Https://Doi.Org/10.5694/J.1326-5377.1996.Tb122012.X

Lawrence Jg, Carapetis Jr, Griffiths K, Edwards K, Condon Jr. Acute Rheumatic Fever And Rheumatic Heart Disease: Incidence And Progression In The Northern Territory Of Australia, 1997 To 2010. Circulation. 2013;128(5):492-501. Doi:10.1161/Circulationaha.113.001477

Hu Y, Tong Z, Huang X, Et Al. The Projections Of Global And Regional Rheumatic Heart Disease Burden From 2020 To 2030. Front Cardiovasc Med. 2022;9. Doi:10.3389/Fcvm.2022.941917

Downloads

Published

2025-02-06